Formal Name: 2-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-(hydroxymethyl)phenyl 2-methylpropanoate fumarate

CAS Number: 286930-03-8

Molecular Formula: C30H41NO7

Formula Weight: 527.65[g/mol]

Stability: 2 years

Storage: -20°C

Purity: 99.0%min (HPLC)

STOCK: Yes

Downloads: 1.Download Chemical Properties of AM-2233. 2.Download the MSDS of AM-2233. Most Popular: JWH-210; JWH-122; JWH-081; AM-2201; AM-1220; AM-2233; JWH-019; 5-APB; Agomelatine; Fesoterodinefumarate

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Formal Name: 2-iodophenyl-(1-(1-methylpiperidin-2-ylmethyl)-1H-indol-3-yl)methanone

Molecular Formula: C22H23IN2O

Formula Weight: 458.3[g/mol]

Stability: 2 years

Storage: -20°C

Purity: 99.0%min (HPLC)

SMILES: CN1CCCCC1CN2C=C(C3=CC=CC=C32)C(=O)C4=CC=CC=C4I

STOCK: Yes

Description:
AM-2233 is a drug which acts as a highly potent full agonist for the cannabinoid receptors, with a Ki of 1.8nM at CB1 and 2.2nM at CB2 as the active (R) enantiomer. It was developed as a selective radioligand for the cannabinoid receptors and has been used as its 131I derivative for mapping the distribution of the CB1 receptor in the brain.

Downloads: 1.Download Chemical Properties of AM-2233. 2.Download the MSDS of AM-2233. Most Popular: JWH-210; JWH-122; JWH-081; AM-2201; AM-1220; AM-2233; JWH-019; 5-APB; Agomelatine; Fesoterodinefumarate

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Formal Name:(R)-(1-((1-methylpiperidin-2-yl)methyl)-1H-indol-3-yl)(naphthalen-1-yl)methanone

CAS Number: 137642-54-7

Molecular Formula: C26H26N2O

Formula Weight: 382.5[g/mol]

Stability: 2 years

Storage: -20°C

Purity: 99.0%min (HPLC)

SMILES: CN1CCCCC1CN2C=C(C3=CC=CC=C32)C(=O)C4=CC=CC5=CC=CC=C54

STOCK: Yes

Description:

AM-1220 is a drug which acts as a potent and moderately selective agonist for the cannabinoid receptor CB1, with around 19x selectivity for CB1 over the related CB2 receptor. It was originally invented in the early 1990s by a team led by Thomas D’Ambra at Sterling Winthrop, but has subsequently been researched by many others, most notably the team led by Alexandros Makriyannis at the University of Connecticut. The (piperidin-2-yl)methyl side chain of AM-1220 contains a stereocenter, so there are two enantiomers with quite different potency, the (R) enantiomer having a Ki of 0.27nM at CB1 while the (S) enantiomer has a much weaker Ki of 217nM. A number of related compounds are known with similar potent cannabinoid activity, with modifications such as substitution of the indole ring at the 2- or 6- positions, the naphthoyl ring substituted at the 4- position or replaced by substituted benzoyl rings or other groups, or the 1-(N-methylpiperidin-2-ylmethyl) group replaced by similar heterocyclic groups such as N-methylpyrrolidin-2-ylmethyl or N-methylmorpholin-3-ylmethyl.

Downloads: 1.Download Chemical Properties of AM-1220. 2.Download the MSDS of AM-1220. Most Popular: JWH-210; JWH-122; JWH-081; AM-2201; AM-1220; AM-2233; JWH-019; 5-APB; Agomelatine; Fesoterodinefumarate

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Formal Name: 5-(2-aminopropyl)benzofuran
1-benzofuran-5-ylpropan-2-amine

Molecular Formula: C11H13NO

Formula Weight: 175.2[g/mol]

Stability: 2 years

Storage: -20°C

Appearance: a light tan coloured powder

Purity: 99.0%min (HPLC)

SMILES: CC(CC1=CC2=C(C=C1)OC=C2)N

STOCK: Yes

Description:
5-APB is also a variant of 6-APB, but at least 30% stronger than 6-APB.
For scientific research purposes only, strictly not for human consumption.

Downloads: 1.Download Chemical Properties of 5-APB. 2.Download the MSDS of 5-APB. Most Popular: JWH-210; JWH-122; JWH-081; AM-2201; AM-1220; AM-2233; JWH-019; 5-APB; Agomelatine; Fesoterodinefumarate

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Synonyms: Valdoxan ®

Formal Name: N-​[2-​(7-​methoxy-​1-​naphthalenyl)ethyl]-​acetamide

CAS Number: 138112-76-2

Molecular Formula: C15H17NO2

Formula Weight: 243.3[g/mol]

Stability: 2 years

Storage: -20°C

Purity: 99.0%min (HPLC)

SMILES: COc1ccc2cccc(CCNC(=O)​C)​c2c1

STOCK: Yes

Description:
Melatonin, produced in the pineal gland, is an endogenous regulator of circadian rhythms. It acts through the melatonin receptors (MT1 and MT2) and has been shown to have anti-depressant activity in experimental models of clinical depression. Agomelatine is a metabolically stable analog of melatonin that displays agonist activity for MT1 and MT2 binding with nanomolar affinity. However, unlike melatonin, agomelatine is a competitive antagonist of human and porcine serotonin (5-HT2C) receptors (pKi = 6.2 and 6.4, respectively) as well as human 5-HT2B receptors (pKi = 6.6). Agomelatine abolishes 5-HT2C agonist effects both in cells and in vivo. It also dose dependently increases extracellular levels of noradrenaline and dopamine in frontal cortex of freely moving rats.

Background Reading:
Yous, S., Andrieux, J., Howell, H.E., et al. Novel naphthalenic ligands with high affinity for the melatonin receptor. J Med Chem 35(8) 1484-1486(1992).

Millan, M.J., Gobert, A., Lejeune, F., et al. The novel melatonin agonist agomelatine (S20098) is an antagonist at 5-hydroxytryptamine2C receptors, blockade of which enhances the activity of frontocortical dopaminergic and adrenergic pathways. J Pharmacol Exp Ther 306(3)954-964 (2003)

Downloads: 1.Download Chemical Properties of Agomelatine. 2.Download the MSDS of Agomelatine. Most Popular: JWH-210; JWH-122; JWH-081; AM-2201; AM-1220; AM-2233; JWH-019; 5-APB; Agomelatine; Fesoterodinefumarate

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Formal Name: [1-​(5-​fluoropentyl)-​1H-​indol-​3-​yl]-​1-​naphthalenyl-​methanone

CAS Number: 335161-24-5

Molecular Formula: C24H22FNO

Formula Weight: 359.4[g/mol]

Stability: 1 years

Storage: -20°C

Purity: 99.2%min (HPLC)

SMILES: O=C(C1=CC=CC2=C1C=CC=C2)​C3=CN(CCCCCF)​C4=CC=CC=C43

STOCK: Yes

Description:
AM2201 is a potent synthetic cannabinoid (CB) with K_i values of 1.0 and 2.6 nM for the CB₁ and CB₂ receptors, respectively. The physiological actions and metabolism of AM2201 have not been characterized.

Downloads: 1.Download Chemical Properties of AM-2201. 2.Download the MSDS of AM-2201. Most Popular: JWH-210; JWH-122; JWH-081; AM-2201; AM-1220; AM-2233; JWH-019; 5-APB; Agomelatine; Fesoterodinefumarate

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273724-21-3

NMR of THIAMINE MONOPHOSPHATE CHLORIDEDIHYDRAT E

273724-21-3

4-(Trifluoromethyl)pyridine-3-carboxylic acid
Molecular Weight : 191.10737 [g/mol]
Molecular Formula: C7H4F3NO2
SMILES: C1=CN=CC(=C1C(F)(F)F)C(=O)O

4-(Trifluoromethyl)nicotinic acid

Ceftazidime;
1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino] acetyl] amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-en-3-yl]methyl]pyridinum hydroxide inner salt

CAS: 72558-82-8

MF: C22H22N6O7S2

Molecular Weight : 420.315223 [g/mol]
Molecular Formula: C21H23BrFNO2
SMILES: Fc1ccc(cc1)C(=O)CCCN1CCC(O)(CC1)c1ccc(Br)cc1
Exact Mass: 401.135427
Molar Volume: 307.5 cm3
Polarizability: 41.15 10-24cm3
Surface Tension: 48.5 dyne/cm
Density: 1.366 g/cm3
Flash Point: 282.6 °C
Enthalpy of Vaporization: 86.51 kJ/mol
Boiling Point: 543.6 °C at 760 mmHg
Vapour Pressure: 1.19E-12 mmHg at 25°C
4-[4-(4-bromophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)butan-1-one
4-(4-(4-bromophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanon
4-(4-(4-bromophenyl)-4-hydroxypiperidino)-4’-fluorobutyrophenone
4-(4-(p-bromophenyl)-4-hydroxypiperidino)-4’-fluoro-butyrophenon
4-(4-(p-bromophenyl)-4-hydroxypiperidino)-4’-fluorobutyrophenone
4-(4-(p-bromophenyl)-4-hydroxypiperidinol)-4’-fluorobutyrophenone
4-[4-(4-BROMOPHENYL)-4-HYDROXY-1-PIPERIDINYL]-1-(4-FLUOROPHENYL)-1-BUTANONE

Bromperidol

10457-90-6

Formal Name: (4-Methyl-1-naphthalenyl)(1-pentyl-1H-indol-3-yl)methanone

CAS Number: 619294-47-2

Molecular Formula: C25H25NO

Formula Weight: 355.5[g/mol]

Stability: 1 years

Storage: -20°C

Purity: 99.0%min (HPLC)

SMILES: CCCCCN1C2=C(C=CC=C2)​C(C(C3=CC=C(C)​C4=C3C=CC=C4)​=O)​=C1

STOCK: Yes

Description:
JWH 122 is a synthetic cannabinoid (CB) that displays high-affinities for both CB₁ (K_i = 0.69 nM) and CB₂ (K_i = 1.2 nM) receptors.

Background Reading:
Huffman, J.W., Mabon, R., Wu, M., et al. 3-indolyl-1-naphthylmethanes: New cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB₁ cannabinoid receptor. Bioorg Med Chem 11539-549 (2003).

Huffman, J.W., Zengin, G., Wu, M., et al. Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB₁ and CB₂receptors: steric and electronic effects of naphthoyl substituents. New highly selective CB₂ receptor agonists. Bioorg Med Chem 13 89-112(2005).

Downloads: 1.Download Chemical Properties of JWH-122. 2.Download the MSDS of JWH-122. Most Popular: JWH-210; JWH-122; JWH-081; AM-2201; AM-1220; AM-2233; JWH-019; 5-APB; Agomelatine; Fesoterodinefumarate

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Formal Name: 4-methoxynaphthalen-1-yl-(1-pentylindol-3-yl)methanone
1-Pentyl-3-(4-methoxynaphthoyl)indole

CAS Number: 210179-46-7

Molecular Formula: C25H25NO2

Formula Weight: 371.47 [g/mol]

Stability: 2 years

Storage: -20°C

Purity: 99.0%min (HPLC)

SMILES: O=C(C1=CN(CCCCC)​C2=C1C=CC=C2)​C3=CC=C(OC)​C4=CC=CC=C43

STOCK: Yes

Description:
JWH 081 is a cannabimimetic indole that shows a high-affinity for the central cannabinoid receptor with a K_i value of 1.2 nM and ten-fold reduced affinity for the peripheral cannabinoid receptor (K_i = 12.4 nM).

Downloads: 1.Download Chemical Properties of JWH-081. 2.Download the MSDS of JWH-081. Most Popular: JWH-210; JWH-122; JWH-081; AM-2201; AM-1220; AM-2233; JWH-019; 5-APB; Agomelatine; Fesoterodinefumarate

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Formal Name: 4-ethylnaphthalen-1-yl-(1-pentylindol-3-yl)methanone

CAS Number: 824959-81-1

Molecular Formula: C26H27NO

Molecular Weight: 369.49868 [g/mol]

Stability: 2 years

Storage: -20°C

Purity: 99.0%min (HPLC)

SMILES: CCCCCN1C=C(C2=CC=CC=C21)C(=O)C3=CC=C(C4=CC=CC=C43)CC

STOCK: Yes

Description:
JWH 210 is a potent cannabimimetic alkylindole, binding the central cannabinoid and peripheral cannabinoid receptors with K_i values of 0.46 and 0.69 nM, respectively. The effects of JWH 210 in whole cells or organisms have not been evaluated.

Downloads: 1.Download Chemical Properties of JWH-210. 2.Download the MSDS of JWH-210. Most Popular: JWH-210; JWH-122; JWH-081; AM-2201; AM-1220; AM-2233; JWH-019; 5-APB; Agomelatine; Fesoterodinefumarate

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Formal Name: (1-​hexyl-​1H-​indol-​3-​yl)-​1-​naphthalenyl-​methanone

CAS Number: 209414-08-4

Molecular Formula: C25H25NO

Formula Weight: 355.5[g/mol]

Stability: 2 years

Storage: -20°C

Purity: 99.0%min (HPLC)

SMILES: CCCCCCn1cc(C(=O)c2cccc3ccccc23)c2ccccc12

STOCK: Yes

Description:
JWH 019 is a cannabimimetic indole that shows a high-affinity for both the central cannabinoid (CB₁) and the peripheral cannabinoid (CB₂) receptors. The affinities of JWH 019 for both CB₁ (K_i = 9.8 nM) and CB₂ (K_i = 5.6 nM) are superior to those of the traditional cannabinoid, Δ⁹-tetrahydrocannabinol (Δ⁹-THC; K_i values of 40.7 and 36.4 nM for CB₁ and CB₂, respectively).

Background Reading:
Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB₁ and CB₂ receptor binding. Drug Alcohol Depend 60 133-140 (2000).

Downloads: 1.Download Chemical Properties of JWH-019. 2.Download the MSDS of JWH-019. Most Popular: JWH-210; JWH-122; JWH-081; AM-2201; AM-1220; AM-2233; JWH-019; 5-APB; Agomelatine; Fesoterodinefumarate

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4-(4-Bromophenyl)-4-(dimethylamino)-1-(2-phenylethyl)cyclohexanol

Molecular Weight : 402.367 [g/mol]
Molecular Formula: C22H28BrNO
SMILES: CN(C)C1(CCC(CC1)(CCC2=CC=CC=C2)O)C3=CC=C(C=C3)Br
Exact Mass: 401.135427
Boiling Point (deg C): 452.51 (Adapted Stein & Brown method)
Melting Point (deg C): 187.23 (Weighted)
VP(mm Hg,25 deg C): 1.03E-010 (Modified Grain method)
Subcooled liquid VP: 5.12E-009 mm Hg (25 deg C, Mod-Grain method)
Water Solubility at 25 deg C (mg/L): 0.2346

Assay (HPLC):  98.3%~98.8%

Melting Range:   110℃ ~ 114℃

Specific Rotation, deg.  -31º ~ -33º

Appearance:  White Crystalline Powder

Solubility 1% In Water:  Readily soluble in water,  almost insoluble in ether

Packing description: Sealed export grade drum & double of sealed plastic bag

Shelf life:  1 years when properly stored

IN STOCK:

Isopropyl-beta-D-thiogalactopyranoside

IPTG, HEMIDIOXANE ADDUCT

IPTG

ISOPROPYL-1-THIO-BETA-D-GALACTOPYRANOSIDE

ISOPROPYLTHIO-BETA-GALACTOSIDE

ISOPROPYLTHIO-BETA-THIOGALACTOSIDASE

ISOPROPYLTHIO-B-THIOGALACTOPYRANOSIDE

ISOPROPYL THIOGALACTOSIDE

ISOPROPYL-BETA-D-THIOGALACTOPYRANOSIDE, DIOXANE FREE

3-(1-(3-(4-fluorobenzoyl)propyl)-1,2,3,6-tetrahydro-4-pyridyl)-1H-benzimidazol-2-one

CAS: 548-73-2

Assay: 98% min

MF: C22H22FN3O2

MW: 379.427

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